Optic nerve glioma in neurofibromatosis-I.

A ten-year-old girl presented with swelling on left upper eyelid, multiple hyper pigmented macules and small nodular swellings with hair growth all over the body since birth. Examination revealed hyper pigmented macules >1 cm in diameter, numerous in numbers on both legs. Hyper pigmented nodular lesion was noted in left temporofacial area and swelling on left upper eyelid with restricted upward movement (Fig 1). Computed tomography (CT) and Magnetic Resonance Imaging (MRI) of orbits revealed bilateral optic nerve glioma (Fig 2). MRI brain showed focal hyper intensities in right dentate nucleus, left cerebral peduncle and bilateral globus pallidus. Hyper intense lesions on T2-weighted MR images of the brain, predominantly located in the basal ganglia, the brainstem and cerebellum are a frequent finding in patients with Neurofibromatosis type-I. Thus, a diagnosis of Neurofibromatosis type-I was made.